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Colloidal Silver Toxicology

2009-07-13

 
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Colloidal Silver (An Analytical - Investigative Report & Theoretical Overview)
 

(6) Colloidal Silver Toxicology

One of the most controversial areas of research regarding colloidal silver / silver mineral water, is regarding toxicity relative to biological systems. This is an area of research that should be given proper attention. To date this is an issue that does not seem to have been given the proper attention it is due. This article addresses this issue from a hypothetical / analytical / theoretical perspective.

Based on material from the historic record, and deductive reasoning, if one takes into account the number of people who allegedly have used various forms of silver mineral water, why aren't there significant numbers of reports of adverse effects if they commonly exist?

If large numbers of people have or may still be using colloidal silver / silver mineral water, and there is significant risk involved in such use, why aren't there many reported incidents of adverse effects / reactions resulting from use or overuse? Logic dictates that if millions of people have used such preparations for extended periods of time, perhaps since the 1970s, then there should be numerous documented reports of such incidents if they are common.

Common sense dictates that; proper research should include documentation regarding how a particular silver preparation being tested was manufactured. Comparisons should be done to establish differences between different forms, so that results regarding one form are not confused between it and another form. A form that is not bound with a protein (a mild silver protein) or other compound (s), should be recognized as different from other forms; such as silver self suspended in water in a colloidal like state, identified as: ( silver mineral water). Each form should be looked at separately from other forms of silver preparations without bias regarding professional research concerning this issue.

The reason "Silver Mineral Water", is also called "Colloidal Silver" even if it is a misnomer, most likely occurred simply because the name first used stuck. The term colloidal silver, is commonly applied to all solutions, gels, compounds etc. that are in a liquid or semi liquid state and containing some form of silver. Though this may not be scientifically accurate, the title colloidal silver is often used. The name colloidal silver apparently was applied to all forms of silver preparations in an effort to describe the reason why it stayed evenly suspended in the liquid without falling out of solution to the bottom of the container. Although the feature of silver being self suspended in an colloidal like state may be similar to other forms of silver preparations, that should be where the similarity to it and other forms of so called silver colloids ends, if proper consideration by the professional researcher is applied.

Silver self suspended in water would be expected to have attributes with regard to toxicity, that are quite different than other forms. Silver preparations that bind the silver to another substance, such as a colloidal gel or protein, silver compounds or silver salts, should be properly identified and isolated with regard to statements made in research conducted and documented.

Argyria is a condition described as a permanent Grey discoloration of the skin. Individuals who have reportedly been effected by this condition seem to represent a few unfortunate incidents. The most notable among such instances were reportedly caused by medical use of silver nitrate, compounds or protein mixtures. Nitrates, compounds and similar formulations would be expected to cause such a condition. For example it is known that forms of silver nitrate will stain anything it comes into contact with, it would not be a surprise from a scientific perspective that such substances would cause argyria. What is hard to imagine is why such a substance would be used on people knowing it would likely cause such a condition.

At the time of this writing, I am not aware of incidents involving silver mineral water having been proved to cause argyria. That said, this does not mean that no such incidents have been alleged, reported or recorded. If you know of documented cases we are interested in knowing about them, and would appreciate getting a copy of such documented cases if available.

Recommended daily allowances have been established for other minerals. For example; safe and effective amounts have been established for Iron. It is also known that although when used in recommended amounts it is safe, exceeding these amounts can not only be harmful but even fatal. For example; "Iron supplement poisoning is the leading cause of poisoning death among children under the age of 6" as stated here: http://jhhs.client.web-health.com/web-health/topics/ChildrensHealth/childrenshealth/iron.html

Even though such severe health risks are in evidence regarding iron supplements, iron supplements are widely used and considered safe in recommended amounts. For example: the average daily allowance for iron is 15 mg a day for females between the ages of 11 and 50. There is10 mg of silver present in a 10 PPM solution of silver, one would have to consume 1.5 liters of a 10 PPM silver solution in order to ingest 15 mg. That may explain why research considerations regarding the ingestion of teaspoon size amounts of 10 PPM silver mineral water are commonly relegated to the field of homeopathy, since the total intake in such cases amounts to fractions of a mg.

The point is that even for already identified safe and effective minerals, some also come with serious safety considerations. What is puzzling is that silver seems to be ostracized from consideration for an RDA. There does not seem to be interest in establishing potential benefit, even though there does not seem to be documentation of serious risk. Even though silver does not appear to be as serious a health risk as iron is, and in spite of the fact that many people seem to believe they derive benefit from its use, it seems that for reasons left to speculation, silver does not appear to be up for serious consideration as a potential health benefit. If current trends regarding silver are used as a gauge I would not expect an RDA to be established any time soon. But that does not mean that serious research that may prove benefit is not being conducted by qualified entities.

There are those who claim that any amount of so called colloidal silver is; risk without benefit. There are also those who believe that using any amount provides benefit without risk. Common sense dictates that the truth once established, is more likely to be found somewhere between these two diametrically opposed perspectives. Only proper research conducted by qualified entities, who address all issues concerned without bias may the truths of the matter be properly established .

The term Argyria, is identified as a condition of a bluish gray color of the skin, and Argosies the bluing of the eye white that is permanent.

There are some researchers who indicate that the risk regarding this issue is not properly understood nor presented. Dr. M. Paul Farber contended that the issue of Argyria was misrepresented and misunderstood, as evidenced by this quote from the book "The Micro Silver Bullet?" by Dr. M. Paul Farber 1996 page XII (ISBN 1-887742-00-X)

In reference to a "Journal of American Medical Association, article, October 18 1995, volume 274 # 15," where cases of Argyria were reportedly cited to have been caused by silver compounds (not colloidal silver).

"These Case history presentations represent biased and unprofessional writing. The author's apparent inability to understand the difference between a silver nitrate, sulfide, or other silver compound demonstrates their lack of understanding basic chemical properties. The matrix, substrate, and particle size are all critical to the varied functions and reactions with use of these products." (End quote)

(Further on the same page)
"That is why there has not been a single case of Argyria from a properly manufactured modern day colloidal sliver product. The cases of Argyria reported in the 1920's and 1930's resulted because the technology of the day was unable to produce a colloidal silver product with a small enough particle size." (End Quote)

(additionally on the same page)

"The diameter of the capillary lumen is 4-9 microns. Therefore the body has no problem in excreting the silver particles." ( End quote)

Reference: "The Micro Silver bullet?" by Dr. M. Paul Farber 1996 page XII (ISBN 1-887742-00-X)

The reported cases of argyria usually referenced from the early 1900's that are commonly sited , generally involve extremely high and frequent doses of silver salts/compounds such as Silver sulfate, silver nitrate or silver chloride. Doses given in those times may have been hundreds or even thousands of times higher than the amounts consumed in current times. The attributes of older preparations were also quite different when compared to products produced using current technology. Therefore; It is important that these points are given proper consideration when doing a literary review of the subject.

Current technology applied to dispersing silver into water, ideally creates nano clusters of silver, a nano cluster is a group of atoms, much smaller than a micron. Not all processes are sensitive to keeping a consistently small nano cluster / particle size. In theory it is important to have consistently small particle size if consistent results are to be achieved. Small particle size is also expected to minimize the issue of toxicity.

During the last several years different approaches to dispersing silver into a colloidal like state have been developed, the preliminary testing of these new approaches has reportedly yielded very interesting results.

Are there practical applications for colloidal silver?

How about inexpensive water filtration? POTTERS FOR PEACE
 

Here are several links regarding research and toxicity in the public domain that may also be useful.

Chronic toxicity data by U.S. EPA.

The EPA regarding web site: "Reach for life colloidal silver information:

http://reach-for-life.com/prodinfo/colsil_iris.htm

 

Toxicity Summary for SILVER

Risk Assessment Information System (RAIS)

http://risk.lsd.ornl.gov/tox/profiles/silver_f_V1.shtml

 

Guidelines for drinking water quality

Extracted from: Guidelines for drinking-water quality, 2nd ed.
Vol. 2. Health criteria and other supporting information.
Geneva, World Health Organization, 1996. pp. 338-343.
http://who.int/water_sanitation_health/GDWQ/Chemicals/silverfull.htm

In closing, all readers should note that this is a hypothetical / analytical / theoretical overview, it is presented for educational purposes only! No claims are made nor implied, with regard to the use of colloidal silver / silver mineral water for medical conditions. Colloidal silver is regulated by the FDA and is not approved as an OTC (over the counter) drug by the FDA. There is no RDA (Recommended Daily Allowance) established, nor is the need, role or safety regarding nutritional use established clinically / scientifically. Therefore; we are not implying nor recommending such use, nor, that anyone self diagnose and treat their own illness using silver or other minerals dispersed into water using the Colloid Silver Master or by any other means. For information regarding potential uses, areas of interest, regulation and related documents please click the "Research" link at the top of this page.

Next Article: Different Forms Of Colloidal Silver

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This information is for educational purposes only and is not to be construed as medical advice. Consult the physician of your choice for medical care and advice.

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